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IN a significant step towards combating antimicrobial resistance( AMR), GSK and the Fleming Initiative unveiled six groundbreaking research programmes, termed ' Grand Challenges ', on Nov 18, 2025.
This collaboration aims to leverage cutting-edge scientific expertise and advanced artificial intelligence( AI) technologies to mitigate the escalating AMR crisis.
The announcement followed the Oct 2025 WHO GLASS Report, which underscored a deteriorating global AMR landscape. The report noted that approximately one in six confirmed bacterial infections stemmed from antibiotic-resistant bacteria, with projected AMR-related deaths expected to rise by 74.5 per cent from 4.71 million in 2021 to 8.22 million by 2050.
All six programmes, fully funded for three years and set to commence by early 2026, encompass critical themes such as: Enhancing the discovery of new antibiotics targeting Gramnegative bacterial infections Accelerating drug discovery for fungal infections. Investigating immune responses to drug-resistant bacteria to foster vaccine research. Developing AI models informed
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AMR FIGHT: Scientists from GSK and the Fleming Initiative join forces to combat antimicrobial resistance using innovative AI technology
by disease surveillance and environmental data to predict the emergence and spread of resistant pathogens. Innovating clinical trials to optimise antibiotic prescription practices. Using international research and insights to guide public policy and engagement, thereby promoting preventative strategies and bolstering R & D efforts against AMR.
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THE World Health Organisation( WHO) announced its first global guidelines to enhance safety, fairness, and affordability in fertility care. This initiative sought to address the pressing public health challenge of infertility, which affects one in six individuals of reproductive age at some point in their lives.
Despite rising global demand for infertility services, access to care remained critically limited. In numerous nations, individuals faced substantial out-of-pocket expenses for tests and treatments, resulting in severe financial burdens. The cost of a single round of in vitro fertilisation( IVF) can exceed double the average annual household income in some regions.
WHO Director-General Dr Tedros Adhanom Ghebreyesus emphasised the urgency of the situation: Infertility is one of the most overlooked public health challenges of our time and a major equity issue globally.
" Millions face this journey alone; priced out of care, pushed toward cheaper but unproven treatments, or forced to choose between their hopes of having children and their financial security."
He urged countries to adopt the new guidelines to foster access to affordable, respectful, and evidence-based care.
The comprehensive guideline includes 40 recommendations to
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HOPE UNLOCKED: WHO ' s landmark guidelines aim to improve access to fertility care for individuals and couples worldwide
improve the prevention, diagnosis, and treatment of infertility. It advocated cost-effective solutions at every stage and called for integrating fertility care into national health strategies, services, and financing structures.- The HEALTH
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